Veterinary Drug Praziquantel Tablets Insect Repellent For Pet And Poultry 100 Pieces

1000 bottles
USD 5-6/bottle
Veterinary Drug Praziquantel Tablets Insect Repellent For Pet And Poultry 100 Pieces
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Common Name: Praziquantel Tablets
Character: This Product Is A White Tablet.
Pharmacological Effects: Broad Spectrum Anti Schistosomiasis And Anti Tapeworm Effects
Animal Type: Pet And Poultry
Packing Bottle: Plastic Medicine Bottles
Main Components: Praziquantel
Basic Infomation
Place of Origin: HENAN CHINA
Brand Name: CXBT & ShowVet
Certification: GMP OEM ISO9001 Veterinary Drug Production License
Model Number: Praziquantel
Payment & Shipping Terms
Packaging Details: Plastic medicine bottles or Customization
Delivery Time: 10-15 working days after payment
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability: 50000bottle/Week
Product Description

Common name: Praziquantel tablets

Main ingredients Praziquantel

Character This product is a white tablet.

Pharmacological effects: Praziquantel has broad-spectrum anti schistosome and anti tapeworm effects. It has extremely high activity against adults of various tapeworms and good activity against larvae;

It has a good repellent effect on schistosomiasis.

The exact mechanism of action of praziquantel on tapeworms has not been determined, and it may be due to its interaction with phospholipids in the parasite envelope, resulting in the outflow of sodium, potassium, and calcium ions. Low concentrations of praziquantel in vitro seem to damage the suction cup function of tapeworms and stimulate their peristalsis, while higher concentrations of drugs can enhance the contraction of the tapeworm chain (segment chain) (irreversible contraction at extremely high concentrations). In addition, praziquantel can cause focal vacuoles to form in specific parts of the tapeworm envelope, which in turn leads to the lysis of the worm body. For schistosomes and trematodes, praziquantel may directly kill the parasite by increasing the flow of calcium ions into the parasite, followed by the formation of focal vacuoles and phagocytosis.
Pharmacokinetics This product is rapidly and almost completely absorbed after oral administration, but has significant first pass effect effect. After medication, dogs and sheep reached their peak blood concentration at 0.5-2 hours and 2 hours, respectively. Intramuscular and subcutaneous injections maintain blood drug concentrations for a longer time than oral administration. Praziquantel is distributed in various tissues throughout the body, with the liver and kidney being the highest, and can cross the blood-brain barrier into the central nervous system. This widely distributed characteristic is beneficial for expelling larvae from various organs of the host (muscles, brain, viscera, and abdominal cavity). Praziquantel, which enters the body, is rapidly metabolized by the liver into inactive monohydroxylated or polyhydroxylated metabolites, mainly excreted in the urine. The elimination half-lives of oral administration are: cattle 7 7 hours, 1.1-2.5 hours for sheep and pigs, 3-3 hours for dogs and rabbits 5 hours. Only a very small amount of prototype drugs (0.1% in sheep) are excreted from urine or feces.

Drug interactions: When combined with albendazole and dexamethasone, the blood concentration of praziquantel can be reduced.

Function and Use Anti helminth drugs. Mainly used for animal schistosomiasis, but also for tapeworm and cysticercosis.

Usage and Dosage Oral administration: One dose, 0.5-1.75 tablets per 10kg body weight for cattle, sheep, and pigs; 0.125-0.25 tablets for dogs and cats; 0.5 to 1 piece of poultry.

[Adverse reactions]
(1) At high doses, cattle occasionally see a slight rise in serum alanine transaminase, and some cattle may experience a rise in body temperature, muscle tremor, and flatulence.

(2) Oral administration in dogs can cause anorexia, vomiting, or diarrhea, but the incidence is less than 5%, and adverse reactions in cats are rare.

(1) Use with caution for puppies under 4 weeks of age and kittens under 6 weeks of age. Products that are compatible with praziquantel and non fe-ntanyl can be used in dogs and cats of all ages, and can also be safely used in pregnant dogs and cats.

[Off medication period] 28 days; The milk abandonment period is 7 days.

[Specification] 0.1g

Packaging 100 pieces/bottle.

Storage Shading and sealed storage.

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